ProGP252 (DgpA)

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ProGP ID ProGP252 (DgpA)
Validation Status Uncharacterized
Organism Information
Organism NameParabacteroides (Bacteroides) distasonis
Domain Bacteria
Classification Phylum : Bacteroidetes
Class : Bacteroidia
Orders : Bacteroidales
Family : Tannerellaceae
Genus : Parabacteroides
Species : distasonis
Taxonomic ID (NCBI) 823
Genome Information
GenBank AB196154
EMBL AB196154
Gene Information
Gene NamedgpA
Protein Information
Protein NameDgpA
Subcellular LocationSurface
Function Most likely to be an S-layer glycoprotein as evidenced by its abundance, its similarity to known S-layers, its surface extraction and presence of an S-layer lattice on the organism.
Glycosylation Status
Technique(s) used for Glycosylation DetectionPro-Q Emerald 300 Glycoprotein staining and AAL (Aleuria aurantia lectin) affinity chromatography
Glycan Information
Glycan Annotation Glycan primarily contains xylose.
Protein Glycosylation linked (PGL) gene(s)
Additional CommentExpression of Dgp glycoproteins is phase-variable in the normal environment of bacteria.
Year of Identification2007
Year of Identification Month Wise2007.02
ReferenceFletcher, C.M., Coyne, M.J., Bentley, D.L., Villa, O.F. and Comstock, L.E., 2007. Phase-variable expression of a family of glycoproteins imparts a dynamic surface to a symbiont in its human intestinal ecosystem. Proceedings of the National Academy of Sciences, 104(7), pp.2413-2418.
Corresponding Author Laurie E. Comstock
ContactChanning Laboratory, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.