ProGP262 (Pillin (Group IV))

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ProGP ID ProGP262 (Pillin (Group IV))
Validation Status Uncharacterized
Organism Information
Organism NamePseudomonas aeruginosa PA7
Domain Bacteria
Classification Phylum : Proteobacteria
Class : gammaproteobacteria
Orders : Pseudomonadales
Family : Pseudomonadaceae
Genus : Pseudomonas
Species : aeruginosa
Strain : PA7
Taxonomic ID (NCBI) 381754
Genome Information
GenBank CP000744.1
EMBL CP000744
Organism Additional Information Pseudomonas aeruginosa is a Gram-negative opportunistic pathogen responsible for nosocomial pneumonia. It possesses a multitude of virulence factors including type IV pili that mediate adhesion to host cells. It is also the major cause of mortality among cystic fibrosis (CF) patients.
Gene Information
Gene NamepilA
Protein Information
Protein NamePillin (Group IV)
Subcellular LocationSecreted
Function Component of pili.
Glycan Information
Glycan Annotation D-Araf (D-arabinofuranose).
Protein Glycosylation linked (PGL) gene(s)
Additional CommentSheared pilins from strain PA7 reacted with anti-LAM antibody, indicating that they are posttranslationally modified with D-Araf.
Year of Identification2008
Year of Identification Month Wise2008.11
ReferenceKus, J.V., Kelly, J., Tessier, L., Harvey, H., Cvitkovitch, D.G. and Burrows, L.L., 2008. Modification of Pseudomonas aeruginosa Pa5196 type IV pilins at multiple sites with d-Ara f by a novel GT-C family arabinosyltransferase, TfpW. Journal of bacteriology, 190(22), pp.7464-7478.
Corresponding Author  Lori L. Burrows
Contact1.Faculty of Dentistry, University of Toronto, Toronto, Ontario, Canada., 2.Department of Biochemistry and Biomedical Sciences, McMaster University 3.The Michael G. DeGroote Institute for Infectious Disease Research, Hamilton, Ontario, Canada L8N 3Z5