ProGP262 (Pillin (Group IV))
Home -> ProGPdb -> Search ProGP -> Display data
| ProGP ID | ProGP262 (Pillin (Group IV)) |
| Validation Status | Uncharacterized |
| Organism Information | |
| Organism Name | Pseudomonas aeruginosa PA7 |
| Domain | Bacteria |
| Classification | Phylum : Proteobacteria Class : gammaproteobacteria Orders : Pseudomonadales Family : Pseudomonadaceae Genus : Pseudomonas Species : aeruginosa Strain : PA7 |
| Taxonomic ID (NCBI) | 381754 |
| Genome Information | |
| GenBank | CP000744.1 |
| EMBL | CP000744 |
| Organism Additional Information | Pseudomonas aeruginosa is a Gram-negative opportunistic pathogen responsible for nosocomial pneumonia. It possesses a multitude of virulence factors including type IV pili that mediate adhesion to host cells. It is also the major cause of mortality among cystic fibrosis (CF) patients. |
| Gene Information | |
| Gene Name | pilA |
| Protein Information | |
| Protein Name | Pillin (Group IV) |
| Subcellular Location | Secreted |
| Function | Component of pili. |
| Glycan Information | |
| Glycan Annotation | D-Araf (D-arabinofuranose). |
| Protein Glycosylation linked (PGL) gene(s) | |
| Additional Comment | Sheared pilins from strain PA7 reacted with anti-LAM antibody, indicating that they are posttranslationally modified with D-Araf. |
| Literature | |
| Year of Identification | 2008 |
| Year of Identification Month Wise | 2008.11 |
| Reference | Kus, J.V., Kelly, J., Tessier, L., Harvey, H., Cvitkovitch, D.G. and Burrows, L.L., 2008. Modification of Pseudomonas aeruginosa Pa5196 type IV pilins at multiple sites with d-Ara f by a novel GT-C family arabinosyltransferase, TfpW. Journal of bacteriology, 190(22), pp.7464-7478. |
| Corresponding Author | Lori L. Burrows |
| Contact | 1.Faculty of Dentistry, University of Toronto, Toronto, Ontario, Canada., 2.Department of Biochemistry and Biomedical Sciences, McMaster University 3.The Michael G. DeGroote Institute for Infectious Disease Research, Hamilton, Ontario, Canada L8N 3Z5 |