ProGP272 (LppL)

Home -> ProGPdb -> Search ProGP -> Display data

ProGP ID ProGP272 (LppL)
Validation Status Uncharacterized
Organism Information
Organism NameMycobacterium tuberculosis
Domain Bacteria
Classification Phylum : Actinobacteria
Class : Actinomycetia
Orders : Corynebacteriales
Family : Mycobacteriaceae
Genus : Mycobacterium
Species : tuberculosis
Taxonomic ID (NCBI) 1773
Genome Information
GenBank AL123456.3
EMBL BX842578
Organism Additional Information It is the causative agent of human tuberculosis. The pathogenesis is influenced by its lipoglycans and glycolipids (having a wide range of immunomodulatory activities), and a variety of its virulence factors and antigens.
Gene Information
Gene NamelppL (Rv2138)
NCBI Gene ID 887303
GenBank Gene Sequence NC_000962.3
Protein Information
Protein NameLppL
UniProtKB/SwissProt ID O06237
NCBI RefSeq NP_216654.1
EMBL-CDSAL123456.3
UniProtKB Sequence >tr|O06237|O06237_MYCTU Lipoprotein, putative OS=Mycobacterium tuberculosis GN=lppL PE=4 SV=1 MLTGNKPAVQRRFIGLLMLSVLVAGCSSNPLANFAPGYPPTIEPAQPAVSPPTSQDPAGA VRPLSGHPRAALFDNGTRQLVALRPGADSAAPASIMVFDDVHVAPRVIFLPGPAAALTSD DHGTAFLAARGGYFVADLSSGHTARVNVADAAHTDFTAIARRSDGKLVLGSADGAVYTLA KNPAVDPASGAATVASRTKIFARVDALVTQGNTTVVLDRGQTSVTTIGADGHAQQALRAG QGATTMAADPLGRVLIADTRGGQLLVYGVDPLILRQAYPVRQAPYGLAGSRELAWVSQTA SNTVIGYDLTTGIPVEKVRYPTVQQPNSLAFDETSDTLYVVSGSGAGVQVIEHAAGTR
Sequence length 358 AA
Function Putative lipoprotein
Glycosylation Status
Technique(s) used for Glycosylation DetectionConcanavalin A (ConA) binding
Literature
Year of Identification2009
Year of Identification Month Wise2009.2
ReferenceGonzález-Zamorano, M., Mendoza-Hernández, G., Xolalpa, W., Parada, C., Vallecillo, A.J., Bigi, F. and Espitia, C., 2009. Mycobacterium tuberculosis glycoproteomics based on ConA-lectin affinity capture of mannosylated proteins. Journal of proteome research, 8(2), pp.721-733.
Corresponding Author Clara Espitia
ContactImmunology Department, Institute of Biomedical Research, National Autonomous University of Mexico, Mexico.