ProGT16.2 (AglH)

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ProGT ID ProGT16.2 (AglH)
Organism Information
Organism NameMethanococcus voltae PS
Domain Archaebacteria
Classification Phylum : Euryarchaeota
Class : Methanococci
Orders : Methanococcales
Family : Methanococcaceae
Genus : Methanococcus
Species : voltae
Strain : PS
Taxonomic ID (NCBI)2188
Genome Information
Gene BankDQ372941.1
Gene Information
Gene NameaglH 
NCBI Reference SequenceDQ372941
Protein information
Protein NameAglH 
Glycosylation Information
Sugar Donor SpecificityUDP-GlcNAc 
Acceptor Substrate SpecificityDolichol-phosphate-disaccharide
Experimental ValidationIn vivo
Donor SpecificityUDP-GlcNAc
Function in Glycosylation pathway1) AglH is a GlcNAc-1-P transferase involved in attachment of a GlcNAc residue to a dolichol lipid carrier in the membrane.
Additional Information1) Mv1751 is a GlcNAc-1-Phosphate transferase able to replaced the essential alg7 gene in S. cerevisiae. 
Year Of Validation2008 
Reference Shams-Eldin, H., Chaban, B., Niehus, S., Schwarz, R.T. and Jarrell, K.F., 2008. Identification of the archaeal alg7 gene homolog (encoding N-acetylglucosamine-1-phosphate transferase) of the N-linked glycosylation system by cross-domain complementation in Saccharomyces cerevisiae. Journal of Bacteriology, 190(6), pp.2217-2220.

Corresponding AuthorDepartment of Microbiology and Immunology, Queens University, Kingston, Ontario, K7L 3N6, Canada.
Reference Larkin, A., Chang, M.M., Whitworth, G.E. and Imperiali, B., 2013. Biochemical evidence for an alternate pathway in N-linked glycoprotein biosynthesis. Nature chemical biology, 9(6), pp.367-373.

Corresponding AuthorDepartment of Life Sciences, Ben Gurion University of the Negev, Beersheva, Israel.