ProGP1152 (SCO4885)

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ProGP ID ProGP1152 (SCO4885)
Validation Status Uncharacterized
Organism Information
Organism NameStreptomyces coelicolor
Domain Bacteria
Classification Phylum : Actinobacteria
Class : Actinomycetia
Orders : Streptomycetales
Family : Streptomycetaceae
Genus : Streptomyces
Species : coelicolor
Taxonomic ID (NCBI) 100226
Genome Information
GenBank AL645882.2
EMBL AL939121
Organism Additional Information Streptomyces coelicolor, a filamentous, high G-C, gram-positive bacteria and are responsible for much of the break down of organic material in the soil as well as the “earthy” smell of soil. Colonies of Streptomyces coelicolor release pigments that are blue/green in alkali and red in acidic conditions, thereby giving the bacterial colonies those colors under the respective conditions
Gene Information
Gene Namesco4885
NCBI Gene ID NC_003888.3
Protein Information
Protein NameSCO4885
UniProtKB/SwissProt ID Q9AK41
NCBI RefSeq CAC33050
UniProtKB Sequence >CAC33050.1 putative lipoprotein [Streptomyces coelicolor A3(2)] MRRISRITVAGAATASLALALAACGGTSTDSGSESKGDKGLAIAYDVGGKGDQSFNDAAYAGLEQAKKEFGYETADVEPTDGETDADKEQRLSSLAKQGYNPVVGIGYAYASAMKNVAAKYPDTTFGIVDDATIEAKNVADLVFNEQEASYLAGVAAAKSTKTNTVGFVGGVDVPLIHKFQAGYEQGVKDTDPKVKVVSQYLTQTAEEGGFSSPDKGKTAAEGQIEKKADVVYAAAGLSGQGVIEAAAANKVWAIGVDSDQYKQEALAKYKDSILTSATKDVAKAVYSLAKSVEDGKPETGIVRGDLKSGEVGLSDSNPKFADDAELQAAIKSAKEKIISGEIKVKSS
Subcellular LocationMembrane protein
Function Solute binding, polysaccharide hydrolases, ABC transporters, enzyme function, cell wall biosynthesis, and maintaining membrane integrity
Glycosylation Status
Glycosylation Type O- (Ser/Thr) linked
Experimentally Validated Glycosite(s ) in Mature Protein>CAC33050.1 putative lipoprotein [Streptomyces coelicolor A3(2)] MRRISRITVAGAATASLALALAACGGTSTDSGSESKGDKGLAIAYDVGGKGDQSFNDAAYAGLEQAKKEFGYETADVEPTDGETDADKEQRLSSLAKQGYNPVVGIGYAYASAMKNVAAKYPDTTFGIVDDATIEAKNVADLVFNEQEASYLAGVAAAKSTKTNTVGFVGGVDVPLIHKFQAGYEQGVKDTDPKVKVVSQYLTQTAEEGGFSSPDKGKTAAEGQIEKKADVVYAAAGLSGQGVIEAAAANKVWAIGVDSDQYKQEALAKYKDSILTSATKDVAKAVYSLAKSVEDGKPETGIVRGDLKSGEVGLSDSNPKFADDAELQAAIKSAKEKIISGEIKVKSS
Technique(s) used for Glycosylation DetectionSDS-PAGE and lectin western blotting
Literature
Year of Identification2019
ReferenceKeenan, T., Dowle, A., Bates, R. and Smith, M.C., 2019. Characterization of the Streptomyces coelicolor glycoproteome reveals glycoproteins important for cell wall biogenesis. Mbio, 10(3), pp.e01092-19.
Corresponding Author Margaret C. M. Smith
ContactDepartment of Biology, University of York, York, United Kingdom