ProGP1213 (BCAL0129 (CheA))

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ProGP ID ProGP1213 (BCAL0129 (CheA))
Validation Status Uncharacterized
Organism Information
Organism NameBurkholderia cenocepacia
Domain Bacteria
Classification Phylum : Proteobacteria
Class : Betaproteobacteria
Orders : Burkholderiales
Family : Burkholderiaceae
Genus : Burkholderia
Species : cenocepacia
Taxonomic ID (NCBI) 95486
Genome Information
GenBank AM747720.1
EMBL AM747720
Organism Additional Information Burkholderia cenocepacia is a species of Gram-negative bacteria that is common in the environment, can form a biofilm with itself, is resistant to many antibiotics[2] and may cause disease in plants
Gene Information
Gene NameBCAL0114
Protein Information
Protein NameBCAL0129 (CheA)
UniProtKB/SwissProt ID B4EE54
NCBI RefSeq CAR50437
UniProtKB Sequence >CAR50437.1 chemotaxis two-component sensor kinase CheA [Burkholderia cenocepacia J2315] MTLDITQFYQTFFDEADELLAQMEQLLLNLDVDAPDPEDLAAIFRAAHSIKGGAATFGFSALTDTTHILESLLDRARNHELTLTKDMVDVFLETKDVLSDQLVDYRASAEPDAAAAAAICAKLERLKAESGAGAPAAAEAAPVAPVAAAAVAPAAEPAAAGDRAPDHVVEQAVAAAHPAADAGAGGPHLKITLVGVDAKDQALLTEELGNLGRIVGREEAGADLSLWVESDVPSDDIVAVCCFVIDESQIRVAHGTAPAAQAAPAAAQDAAAAVAAEPAAAPPPARVEVFAPQAAAAQPAASAPAEPAAAAAAQPQPPSPSQQHAQPQPAEHAAPAAAHHDDKRARPAAAAAAGAEGSSIRVGVEKVDQLINLVGELVITQAMLAETASAFDPALHDRLFNGMAQLERNARDLQEAVMSIRMMPMDYVFSRFPRLVRDLAGKLGKQVELVTFGQATELDKSLIERIIDPLTHLVRNSLDHGIETVDKRVAAGKDAVGQLVLSAAHHGGNIVIEVSDDGAGLNRERILAKAAKQGMQIAENISDDEVWQLIFAPGFSTAETVTDVSGRGVGMDVVKRNIQSMGGHVEITSLAGRGTTTRIVLPLTLAILDGMSVKVGSEIFILPLNFVMESLQPSNDDIYTVGNGERVVRVRGEYLPLVALHEVFSVEDARTDPTQGIVTIMETEGRRFAMLIDELVGQQQVVVKNLETNYRKVHGISAATILGDGSVALIVDVAALNRETRATHGARAGAELAVF
Function flagellum-mediated motility and chemotaxis
Glycosylation Status
Glycosylation Type O- (Ser/Thr) linked
Experimentally Validated Glycosite(s ) in Mature Protein>CAR50437.1 chemotaxis two-component sensor kinase CheA [Burkholderia cenocepacia J2315] MTLDITQFYQTFFDEADELLAQMEQLLLNLDVDAPDPEDLAAIFRAAHSIKGGAATFGFSALTDTTHILESLLDRARNHELTLTKDMVDVFLETKDVLSDQLVDYRASAEPDAAAAAAICAKLERLKAESGAGAPAAAEAAPVAPVAAAAVAPAAEPAAAGDRAPDHVVEQAVAAAHPAADAGAGGPHLKITLVGVDAKDQALLTEELGNLGRIVGREEAGADLSLWVESDVPSDDIVAVCCFVIDESQIRVAHGTAPAAQAAPAAAQDAAAAVAAEPAAAPPPARVEVFAPQAAAAQPAASAPAEPAAAAAAQPQPPSPSQQHAQPQPAEHAAPAAAHHDDKRARPAAAAAAGAEGSSIRVGVEKVDQLINLVGELVITQAMLAETASAFDPALHDRLFNGMAQLERNARDLQEAVMSIRMMPMDYVFSRFPRLVRDLAGKLGKQVELVTFGQATELDKSLIERIIDPLTHLVRNSLDHGIETVDKRVAAGKDAVGQLVLSAAHHGGNIVIEVSDDGAGLNRERILAKAAKQGMQIAENISDDEVWQLIFAPGFSTAETVTDVSGRGVGMDVVKRNIQSMGGHVEITSLAGRGTTTRIVLPLTLAILDGMSVKVGSEIFILPLNFVMESLQPSNDDIYTVGNGERVVRVRGEYLPLVALHEVFSVEDARTDPTQGIVTIMETEGRRFAMLIDELVGQQQVVVKNLETNYRKVHGISAATILGDGSVALIVDVAALNRETRATHGARAGAELAVF
Literature
Year of Identification2020
ReferenceOppy, C.C., Jebeli, L., Kuba, M., Oates, C.V., Strugnell, R., Edgington-Mitchell, L.E., Valvano, M.A., Hartland, E.L., Newton, H.J. and Scott, N.E., 2019. Loss of O-linked protein glycosylation in Burkholderia cenocepacia impairs biofilm formation and siderophore activity and alters transcriptional regulators. Msphere, 4(6), pp.e00660-19.
Corresponding Author Nichollas E Scott
ContactDepartment of Microbiology and Immunology, University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, Australia