ProGP203 (Cell envelope glycoprotein)
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| ProGP ID | ProGP203 (Cell envelope glycoprotein) |
| Validation Status | Uncharacterized |
| Organism Information | |
| Organism Name | Streptomyces coelicolor A3(2) |
| Domain | Bacteria |
| Classification | Phylum : Actinobacteria Class : Actinomycetia Orders : Streptomycetales Family : Streptomycetaceae Genus : Streptomyces Species : coelicolor Strain : A3(2) |
| Taxonomic ID (NCBI) | 100226 |
| Genome Information | |
| GenBank | NC_003888.3 |
| EMBL | AL939115 |
| Organism Additional Information | Streptomyces coelicolor is a filamentous bacterium responsible for the production of most natural antibiotics for human and veterinary use. |
| Protein Information | |
| Protein Name | Cell envelope glycoprotein |
| UniProtKB/SwissProt ID | Q8CJY7 |
| EMBL-CDS | AAM78434.1 |
| UniProtKB Sequence | >tr|Q8KVT6|Q8KVT6_STRCO Putative secreted protein (Fragment) OS=Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) GN=ecrD PE=4 SV=1 TGILSLCGSPALADSHADGAATNSPGAVSGNALQVPVDVPVNACGNTVDVIAALNPAFGN ECENASDEKTDGHGGGYGEDASSSSSSSTSASSSGSHADGATEGSPGVGSGNNAQVPVDV PVNLCGNTVDVIAALNPVFGNKCENDAEEPPGYGEEEPPPPTTPPGYGEEEPPPPTHEEP PPPSGEEEPPPPSEEEHTPPAPQTEQPPALAETGSEGTLGAAAAGAVLIAGGAILYRRGR |
| Sequence length | 240 AA |
| Subcellular Location | Cell wall associated |
| Function | It acts as a phage receptor for (phi)C31. |
| Glycosylation Status | |
| Glycosylation Type | O- (Ser/Thr) linked |
| Technique(s) used for Glycosylation Detection | Concanavalin A-binding |
| Protein Glycosylation linked (PGL) gene(s) | |
| Additional Comment | Genes encoding homologs to the eukaryotic dolichol-phosphate-D-mannose, protein O-D-mannosyltransferase (SCO3154, Pmt), and dolichol-phosphate-mannose synthase (SCO1423, Ppm1) been found to be essential for phage (phi)C31 infection and sensitivity in S. coelicolor. Glycosylation has a role in the infection by phage. |
| Literature | |
| Year of Identification | 2001 |
| Year of Identification Month Wise | 2001.7 |
| Reference | Cowlishaw, D.A. and Smith, M.C., 2002. A gene encoding a homologue of dolichol phosphate-β-d-mannose synthase is required for infection of Streptomyces coelicolor A3 (2) by phage φC31. Journal of bacteriology, 184(21), pp.6081-6083. |
| Corresponding Author | Margaret C. M. Smith |
| Contact | Institute of Genetics, University of Nottingham, Queens Medical Centre, Nottingham NG7 2UH, United Kingdom. |
| Reference | Cowlishaw, D.A. and Smith, M.C., 2001. Glycosylation of a Streptomyces coelicolor A3 (2) cell envelope protein is required for infection by bacteriophage φC31. Molecular microbiology, 41(3), pp.601-610. |
| Corresponding Author | Margaret C. M. Smith |
| Contact | Institute of Genetics, University of Nottingham, Queens Medical Centre, Nottingham NG7 2UH, United Kingdom. |