ProGP465 (Immunogenic protein MPT63)
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| ProGP ID | ProGP465 (Immunogenic protein MPT63) |
| Validation Status | Uncharacterized |
| Organism Information | |
| Organism Name | Mycobacterium smegmatis mc2-155 |
| Domain | Bacteria |
| Classification | Phylum : Actinobacteria Class : Actinomycetia Orders : Corynebacteriales Family : Mycobacteriaceae Genus : Mycobacterium Species : smegmatis Strain : mc(2)155 |
| Taxonomic ID (NCBI) | 246196 |
| Genome Information | |
| GenBank | CP000480.1 |
| EMBL | CP000480.1 |
| Gene Information | |
| Gene Name | Msmeg_828 |
| NCBI Gene ID | 4537086 |
| GenBank Gene Sequence | NC_008596.1 |
| Protein Information | |
| Protein Name | Immunogenic protein MPT63 |
| UniProtKB/SwissProt ID | A0QQP4 |
| NCBI RefSeq | WP_011727224.1 |
| EMBL-CDS | ABK74260.1 |
| UniProtKB Sequence | >tr|A0QQP4|A0QQP4_MYCS2 Immunogenic protein MPT63 OS=Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) GN=MSMEG_0828 PE=4 SV=1 MKISQLTIAAAAALAISGAAGTAGMATAFAEAAQAAQVSANPLGSQARLENGDVVQAWTI SDLKPSSDPIPYAVQGTLWEATATDEAVSGSVIPIVSNLNARAANGENYRVLFQVATPQG VNPSTLAPGQKTTGKVYFDVTGEAPTTVVYNDGERDLLAWSQTAASTTSPRPAATGSGTS ASTPARTAPVTTAPASNTPATELVPESPAVAPTGAAPAAAPGAGAAATDIPGSTVPPLAE DAADEALAEELTEDLPDELSQDSVTPGESVGTPLPAAVQQAPAAPAPGQPAPAAPGAQDI PAAPAGEVPAAPVTPAPAAPVDGSTTPTVPAGSDAPLTAGGIPTLVPAANPGAPTP |
| Sequence length | 356 AA |
| Subcellular Location | Extracellular space |
| Glycosylation Status | |
| Glycosylation Type | O- (Ser/Thr) linked |
| Technique(s) used for Glycosylation Detection | LC-MS (HCD) |
| Glycan Information | |
| Glycan Annotation | Monosaccharide ( mannose) |
| Protein Glycosylation linked (PGL) gene(s) | |
| OST ProGT ID | ProGT61 ProGT62 |
| Characterized Accessory Gene(s) | Msmeg_5447 |
| Literature | |
| Year of Identification | 2013 |
| Year of Identification Month Wise | 2014.3.5 |
| Reference | Liu, C.F., Tonini, L., Malaga, W., Beau, M., Stella, A., Bouyssié, D., Jackson, M.C., Nigou, J., Puzo, G., Guilhot, C. and Burlet-Schiltz, O., 2013. Bacterial protein-O-mannosylating enzyme is crucial for virulence of Mycobacterium tuberculosis. Proceedings of the National Academy of Sciences, 110(16), pp.6560-6565. |
| Corresponding Author | Michel Rivière |
| Contact | University of Toulouse, Paul Sabatier University, Institute of Pharmacology and Structural Biology, F-31077 Toulouse, France; |