| ProGT ID | ProGT10.2 (PglA) |
| Organism Information | |
| Organism Name | Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168) |
| Domain | Bacteria |
| Classification | Phylum : Proteobacteria Class : Epsilonproteobacteria Orders : Campylobacterales Family : Campylobacteraceae Genus : Campylobacter Species : jejuni Subspecies : jejuni Strain : ATCC 700819 / NCTC 11168 |
| Taxonomic ID (NCBI) | 192222 |
| Genome Information | |
| Gene Bank | AL111168.1 |
| EMBL | AL111168.1 |
| Gene Information | |
| Gene Name | pglA |
| NCBI Gene ID | 905416 |
| NCBI Reference Sequence | NC_002163.1. |
| Protein information | |
| Protein Name | PglA |
| UniProtKB/ SwissProt ID | Q0P9C9 |
| NCBI Ref Seq | WP_002852885.1. |
| UniProtKB Sequence | >sp|Q0P9C9|PGLA_CAMJE N,N'-diacetylbacillosaminyl-diphospho-undecaprenol alpha-1,3-N-acetylgalactosaminyltransferase OS=Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168) GN=pglA PE=1 SV=1 MRIGFLSHAGASIYHFRMPIIKALKDRKDEVFVIVPQDEYTQKLRDLGLKVIVYEFSRAS LNPFVVLKNFFYLAKVLKNLNLDFIQSAAHKSNTFGILAAKWAKIPYRFALVEGLGSFYI DQGFKANLVRFVINSLYKLSFKFAHQFIFVNESNAEFMRNLGLKENKICVIKSVGINLKK FFPIYVESEKKELFWKNLNIDKKPIVLMIARALWHKGVKEFYESATMLKDKANFVLVGGR DENPSCASLEFLNSGAVHYLGARSDIVELLQNCDIFVLPSYKEGFPVSVLEAKACGKAIV VSDCEGCVEAISNAYDGLWAKTKNAKDLSEKISLLLEDEKLRLNLAKNAAQDALQYDENI IAQRYLKLYDRVIKNV |
| EMBL CDS | CAL35242.1. |
| Sequence length | 376 AA |
| String | 192222.Cj1125c. |
| Glycosylation Information | |
| CAZY Family | GT4 |
| EC Number (BRENDA) | 2.4.1.290 |
| Sugar Donor Specificity | UDP-GalNAc |
| Acceptor Substrate Specificity | UndPP-diNAcBac |
| Experimental Validation | In vivo and In vitro |
| Product | UndPP-diNAcBac-GalNAc |
| Donor Specificity | UDP-GalNAc |
| Function in Glycosylation pathway | 1) PglA is a GalNAc transferase and adds the first GalNAc residues to the Campylobacter jejuni glycan. |
| Additional Information | 1) PglA is very specific enzyme other than Und-PP-Bac, it also accepts Und-PP-6-hydroxybacillosamine and Und-PP-GlcNAc to lesser extents. |
| Litrature | |
| Year Of Validation | 2005 |
| Reference | Glover, K.J., Weerapana, E. and Imperiali, B., 2005. In vitro assembly of the undecaprenylpyrophosphate-linked heptasaccharide for prokaryotic N-linked glycosylation. Proceedings of the National Academy of Sciences, 102(40), pp.14255-14259. |
| Corresponding Author | Departments of Chemistry and Biology, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139 |