ProGT15.1 (AglD)

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ProGT ID ProGT15.1 (AglD)
Organism Information
Organism NameHaloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 /DS2)
Domain Archaebacteria
Classification Phylum : Euryarchaeota
Class : Halobacteria
Orders : Haloferacales
Family : Haloreacaceae
Genus : Haloferax
Species : volcanii
Strain : strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 /DS2
Taxonomic ID (NCBI)309800
Genome Information
Gene BankCP001956.1
EMBLCP001956.1
Gene Information
Gene NameaglD 
NCBI Gene ID8924085
NCBI Reference SequenceNZ_AOHU01000097.1.
Protein information
Protein NameAglD 
UniProtKB/ SwissProt IDD4GUA0
NCBI Ref SeqWP_004044138.1.
UniProtKB Sequence>sp|D4GUA0|AGLD_HALVD Glycosyltransferase AglD OS=Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) GN=aglD PE=1 SV=1 MGRPTERRPAAATAAGVEVSVVLPAYNEARTIENTVRVTVETLESFLPADAFEVIVAEDG CDDETPEIADRLAAEDDRIRHYHSDDRLGRGGALERAFEAARGDTLVYFDTDLATDMRHL EELVERVRSGEYDAATGSRWMPDRVADRPRKRGVPSRAYNGLVRLFLRSDLRDHQCGFKA FSREAFEALRDDVEDNHWFWDTEMLVRAQRAGFRVAEFPVDWEPKGDTKVDLVRDILGMG SQILRTWWQLTVRPRITRRVTIVAGLLLTVLALALMTLYIDPSEVISVLGDADPALVAAA AVIYVVSWPLRGIRYREILRELGYREKAGFLTGAIFISQTGNLVFPARAGDAVRAYVVKA RRNIPYPSGFASLAVERVFDLLTIAGLAGVVLVGLAATGGLDDIATVLATGVSGGSVDVS ADDVRTAAYVATGVGVVAILGVLGIALSARADRNVVRAFVGRFSSDSYVELVAGVIEQFV SDLQAVAGNRAAFGRVGLTSLAIWTVDVVTAVVVLLALGVDIDPVVLVGVSFFAVSVGNL AKVLPLSPGGVGLYEIAFTVFMAALAPVTPAAALAAAVLDHAVKNAVTIVGGVGSMLSLN VSLTTAVEESAEVRDREHELADSK
EMBL CDSCAM91696.1.
Sequence length324 AA
Subcellular LocationMembrane (Integral component of membrane)
String309800.HVO_0798.
Glycosylation Information
CAZY FamilyGT2
EC Number (BRENDA)2.4.1.-
Sugar Donor SpecificityUDP-hexuronic acid 
Acceptor Substrate SpecificityDolichol phosphate-linked trisaccharide
Experimental ValidationIn vivo
ProductDolichol phosphate-hexose
Donor SpecificityUDP-hexuronic acid
Function in Glycosylation pathway1) AglD transfer hexose subunit to form the pentasaccharide. Hexose is mannose, mannose addition to DolP
Additional InformationIt is DolP-(Mannose) Synthase participate in N-glycosylation pathway 
Litrature
Year Of Validation2006 
Reference Abu-Qarn, M., Yurist-Doutsch, S., Giordano, A., Trauner, A., Morris, H.R., Hitchen, P., Medalia, O., Dell, A. and Eichler, J., 2007. Haloferax volcanii AglB and AglD are involved in N-glycosylation of the S-layer glycoprotein and proper assembly of the surface layer. Journal of molecular biology, 374(5), pp.1224-1236.

Corresponding AuthorDepartment of Life Sciences, Ben Gurion University of the Negev, Beersheva, Israel.
Reference Zaretsky, M., Guan, Z., Zarivach, R. and Eichler, J., 2022. Distinct Regions of the Haloferax volcanii Dolichol Phosphate-Mannose Synthase AglD Mediate the Assembly and Subsequent Processing of the Lipid-Linked Mannose. Journal of Bacteriology, 204(1), pp.e00447-21.

Corresponding AuthorDepartment of Life Sciences, Ben-Gurion University of the Negev, Beersheva, Israel