ProGT ID | ProGTNC16 (PglD) |
Organism Information | |
Organism Name | Neisseria gonorrhoeae MS11 |
Domain | Bacteria |
Classification | Phylum : Proteobacteria Class : Betaproteobacteria Orders : Neisseriales Family : Neisseriaceae Genus : Neisseria Species : gonorrhoeae Strain : MS11 |
Taxonomic ID (NCBI) | 528354 |
Genome Information | |
Gene Bank | CP003909.1 |
EMBL | CP003909.1 |
Gene Information | |
Gene Name | pglD |
Protein information | |
Protein Name | PglD |
Glycosylation Information | |
CAZY Family | Non-GT |
EC Number (BRENDA) | 1.1.1.- |
Experimental Validation | In vitro |
Function in Glycosylation pathway | 1) PglD is a NADH-dependent dehydratase, required for the synthesis of Und-PP-diNAcBac in N. gonorrhoeae. |
Additional Information | 1) It shows homology with PglF of C. jejuni and used UDP-GlcNAc as a substrate. |
Litrature | |
Year Of Validation | 2011 |
Reference | Hartley, M.D., Morrison, M.J., Aas, F.E., Børud, B., Koomey, M. and Imperiali, B., 2011. Biochemical characterization of the O-linked glycosylation pathway in Neisseria gonorrhoeae responsible for biosynthesis of protein glycans containing N, N?-diacetylbacillosamine. Biochemistry, 50(22), pp.4936-4948. |
Corresponding Author | Departments of Chemistry and Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA. |