ProGT128 (Nss)

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ProGT ID ProGT128 (Nss)
Organism Information
Organism NameStreptococcus gordonii
Clinical ImplicationPathogenic
Classification Phylum : Firmicutes
Class : Bacilli
Orders : Lactobacillales
Family : Streptococcaceae
Genus : Streptococcus
Species : gordonii
Taxonomic ID (NCBI)1302
Genome Information
Gene Bank AY028381.5
Gene Information
Gene Namenss
Protein information
Protein NameNss 
Function in Native Organism Nss adds Glc to the GlcNAc residues (G2 species) of GspB enzyme
Glycosyltransferase Information
Glycosylation TypeO- (Ser/Thr) linked 
CAZY FamilyGT113
Mechanism of Glycan TransferSequential
Donor TypeUDP-Glc
Donor SpecificityNucleotide activated sugars
Glycan Information
Glycan transferredMonosaccharides (Glc) 
Method of Glycan IndentificationWestern Blotting
Experimental_strategies in vitro 
Acceptor Subtrate Information
Acceptor Substrate name GspB
ProGPdb ID ProGP229 (GspB)
Year Of Validation2018 
Reference Chen, Y., Bensing, B.A., Seepersaud, R., Mi, W., Liao, M., Jeffrey, P.D., Shajahan, A., Sonon, R.N., Azadi, P., Sullam, P.M. and Rapoport, T.A., 2018. Unraveling the sequence of cytosolic reactions in the export of GspB adhesin from Streptococcus gordonii. Journal of Biological Chemistry, 293(14), pp.5360-5373.

Corresponding AuthorHoward Hughes Medical Institute, Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02115