ProGT133 (GT)
| ProGT ID | ProGT133 (GT) |
| Organism Information | |
| Organism Name | Listeria monocytogenesis SLCC2540 |
| Clinical Implication | Pathogenic |
| Domain | Bacteria |
| Classification | Phylum : Firmicutes Class : Bacilli Orders : Bacillales Family : Listeriaceae Genus : Listeria Species : monocytogenes Strain : SLCC2540 |
| Taxonomic ID (NCBI) | 879089 |
| Genome Information | |
| Gene Bank | FR733645.1 |
| Gene Information | |
| Protein information | |
| Protein Name | GT |
| Function in Native Organism | Found in glycocin biosynthesis cluster and transfer the sugar to the glycocin, which is required for the antimicrobial activity |
| Glycosyltransferase Information | |
| Glycosylation Type | O- (Ser) linked |
| CAZY Family | GT2 |
| Mechanism of Glycan Transfer | Sequential |
| Donor Type | UDP-Glc |
| Donor Specificity | Nucleotide activated sugars |
| Glycan Information | |
| Glycan transferred | Monosaccharides (Glc) |
| Method of Glycan Indentification | MS/MS analysis |
| Experimental_strategies | In vivo |
| Acceptor Subtrate Information | |
| Acceptor Substrate name | Listeriocytocin |
| ProGPdb ID | ProGP700 (Listeriocytocin) |
| Litrature | |
| Year Of Validation | 2018 |
| Reference | Ren, H., Biswas, S., Ho, S., Van Der Donk, W.A. and Zhao, H., 2018. Rapid discovery of glycocins through pathway refactoring in Escherichia coli. ACS chemical biology, 13(10), pp.2966-2972. |
| Corresponding Author | 1. Department of Chemical and Biomolecular Engineering, University of Illinois at UrbanaChampaign, Urbana, IL 61801
2. Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801
4. Department of Bioengineering, University of Illinois at Urbana-Champaign, Urbana, IL 61801
5. Howard Hughes Medical Institute, University of Illinois at Urbana-Champaign, Urbana, IL 61801
6. Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL 61801 |