ProGT134 (PalS)
ProGT ID | ProGT134 (PalS) |
Organism Information | |
Organism Name | Aeribacillus pallidus 8 |
Domain | Bacteria |
Classification | Phylum : Firmicutes Class : Bacilli Orders : Bacillales Family : Bacillaceae Genus : Aeribacillus Species : pallidus Strain : 8 |
Taxonomic ID (NCBI) | 33936 |
Genome Information | |
Gene Bank | LVHY01000134.1 |
Gene Information | |
Gene Name | palS |
Protein information | |
Protein Name | PalS |
Function in Native Organism | Found in glycocin biosynthesis cluster and transfer the sugar to the glycocin, which is required for the antimicrobial activity |
Additional Information | Also used as a glycoengineering tool to transfer the sugar glucose to the glycocins (Hyp1 and Hyp2) present in glycocin biosynthesis clusters of other bacteria Bacillus megaterium BHG1 Bacillus sp. JCM19047 |
Glycosyltransferase Information | |
Glycosylation Type | S- (Cys) linked |
CAZY Family | GT2 |
Mechanism of Glycan Transfer | Sequential |
Donor Type | UDP-Glc |
Donor Specificity | Nucleotide activated sugars |
Glycan Information | |
Glycan transferred | Monosaccharides (Glc) |
Method of Glycan Indentification | LC-ESI-QMS/MS mass spectrometery |
Experimental_strategies | In vivo |
Acceptor Subtrate Information | |
Acceptor Substrate name | PalA |
ProGPdb ID | ProGP703 (PalA) |
Acceptor Substrate name | Hyp1 |
ProGPdb ID | ProGP699 (Hyp1) |
Acceptor Substrate name | Hyp2 |
ProGPdb ID | ProGP700 (Hyp2) |
Litrature | |
Year Of Validation | 2019 |
Reference | Kaunietis, A., Buivydas, A., ?itavi?ius, D.J. and Kuipers, O.P., 2019. Heterologous biosynthesis and characterization of a glycocin from a thermophilic bacterium. Nature communications, 10(1), pp.1-12. |
Corresponding Author | 1. Molecular Genetics Dept., Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Nijenborgh 7, 9747 AG Groningen, Netherlands |