ProGT135 (RbmD)
| ProGT ID | ProGT135 (RbmD) |
| Organism Information | |
| Organism Name | Vibrio cholerae |
| Clinical Implication | Pathogenic |
| Domain | Bacteria |
| Classification | Phylum : Proteobacteria Class : GammaProteobacteria Orders : Vibrionales Family : Vibrionaceae Genus : Vibrio Species : cholerae |
| Taxonomic ID (NCBI) | 666 |
| Genome Information | |
| Gene Information | |
| Protein information | |
| Protein Name | RbmD |
| Function in Native Organism | It is a protein with structural similarities to PglLVc and other established oligosaccharyltransferases (OTases) of this bacteria |
| Additional Information | RbmD generally affect secretion of T2SS-dependent substrates including chitinases, its mutants exhibit altered growth on chitin. |
| Glycosyltransferase Information | |
| Glycosylation Type | O- (Ser/Thr) linked |
| Mechanism of Glycan Transfer | En bloc |
| Donor Type | Und-PP-diNAcBac |
| Donor Specificity | Lipid linked sugars |
| Glycan Information | |
| Glycan transferred | Und-PP-diNAcBac |
| Method of Glycan Indentification | LC-MS/MS |
| Experimental_strategies | In vivo and In vitro |
| Acceptor Subtrate Information | |
| Acceptor Substrate name | DegP |
| ProGPdb ID | ProGP1158 (DegP) |
| Litrature | |
| Year Of Validation | 2019 |
| Reference | Vorkapic, D., Mitterer, F., Pressler, K., Leitner, D.R., Anonsen, J.H., Liesinger, L., Mauerhofer, L.M., Kuehnast, T., Toeglhofer, M., Schulze, A. and Zingl, F.G., 2019. A broad spectrum protein glycosylation system influences type II protein secretion and associated phenotypes in Vibrio cholerae. Frontiers in microbiology, 10, p.2780. |
| Corresponding Author | 1. Institute of Molecular Biosciences, University of Graz, Graz, Austria |