ProGT144 (Maf4)
| ProGT ID | ProGT144 (Maf4) |
| Organism Information | |
| Organism Name | Campylobacter jejuni 11168 |
| Clinical Implication | Pathogenic |
| Domain | Bacteria |
| Classification | Phylum : Proteobacteria Class : EpsilonProteobacteria Orders : Campylobacterales Family : Campylobacteraceae Genus : Campylobacter Species : jejuni |
| Taxonomic ID (NCBI) | 197 |
| Genome Information | |
| Gene Bank | AL111168.1 |
| Gene Information | |
| Gene Name | maf4 |
| Protein information | |
| Protein Name | Maf4 |
| UniProtKB/ SwissProt ID | Q0P8S3 |
| NCBI Ref Seq | ACC77728.1 |
| UniProtKB Sequence | >tr|Q0P8S3|Q0P8S3_CAMJE Uncharacterized protein OS=Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168) OX=192222 GN=maf4 PE=4 SV=1 MTFTPTQKELFNKNIEALNNILLKESLKEIKSSKFELILGKDNLDINLKDTSIKNNGGGG YNENLLYQDPIKELQTMLNTYNDKYLLYPVLYFYGFGNGILFKALLQNKNHQHIVVFEKD IEIIWVIFHILDFSNELQNARLMVLENDKLQTQDYTELCSSKPFFQFSRIYFLELMSHYY ERFHEDVLELNKKLAENFKNIILRNGNDPKDALQGIEQFVYNLPQMITHPSYKELLSKRK NLSDTAIIVSTGPSLTKQLPLLKKYASKATIFCADSSYPILAKHGIKPDYVCMLERTELT AEFFNHDFGEFDKDIVFICAGVVHPKAIEYLKGRNLVITQKVLAFPYYINLKDFSYAAVG LSVAHTLSYLATYLSHKNIIFIGQDLAYAENGNSHPDDYQNSANYESQMYEHILTEAYGG NGKVETHSIWLLFKNWFENEMIPNTRKMGITTYNCTEGGARIEGTIEKPFLWACENLLDK DLNKPFEKLEPLSLNKQNEFLLKAYYKVYQSIKHCRDFSKILSNDFNNIQNIYLNLNKKE NDLNLAIRKIDEFKNKLENIKQMQDLYEILQPLRTQFELNLARIYVLNPKTKEDAFNKSI LWIKEHLEFMELVYGHIKAQENALIKNILPLEEKLKERKLDKWMERVRR |
| Sequence length | 649 AA |
| Subcellular Location | Flagella |
| Function in Native Organism | It is helpful in motility and invasiveness. |
| Glycosyltransferase Information | |
| Glycosylation Type | O- (Ser/Thr) linked |
| Mechanism of Glycan Transfer | Sequential |
| Donor Type | CMP-Leg |
| Donor Specificity | Nucleotide activated sugars |
| Glycan Information | |
| Glycan transferred | Monosaccharide (Leg) |
| Method of Glycan Indentification | Western blot & UPLC-MS detection |
| Experimental_strategies | In vivo |
| Acceptor Subtrate Information | |
| Acceptor Substrate name | Flagella |
| ProGPdb ID | ProGP1285 (Flagella) |
| Litrature | |
| Year Of Validation | 2021 |
| Reference | Meng, X., Boons, G.J., Wösten, M.M. and Wennekes, T., 2021. Metabolic labeling of legionaminic acid in flagellin glycosylation of Campylobacter jejuni identifies Maf4 as a putative legionaminyl transferase. Angewandte Chemie International Edition, 60(47), pp.24811-24816. |
| Corresponding Author | Department of Chemical Biology and Drug DiscoveryUtrecht Institute for Pharmaceutical Sciences andBijvoet Center for Biomolecular Research, Utrecht UniversityUniversiteitsweg 99, 3584 CG Utrecht (The Netherlands) |