| Organism Information |
| Organism Name | Neisseria meningitidis 8013 |
| Clinical Implication | Pathogenic |
| Domain | Bacteria |
| Phylum | Proteobacteria |
| Classification | Family: Neisseriaceae
Order: Neisseriales
Class: Betaproteobacteria
Division or phylum: "Proteobacteria" |
| Taxonomic ID (NCBI) | 604162 |
| Genome Information |
| Gene Bank | FM999788 |
| EMBL | FM999788 |
| Gene Information |
| Protein information |
| Protein Name | PglL |
| Subcellular Location | Membrane (Integral component of membrane) |
| Additional Information | 1) PglL can use UDP-diNacBAc as substrate instead of UDP-GlcNAc or UDP-GalNAc in vitro. |
| Glycosyltransferase Information |
| Glycosylation Type | O- (Ser/Thr) linked |
| EC Number (BRENDA) | 2.4.1.- |
| Mechanism of Glycan Transfer | En bloc |
| Donor Type | Lipid linked sugars |
| Donor Specificity | UDP-diNacBAc |
| Accessory GT ID | ProGT24.1 ProGT24.2 ProGT24.3 ProGT24.4 |
| Glycan Information |
| Glycan transferred | 2,4-diacetamido-2,4,6-trideoxyhexose (GATDH) |
| Method of Glycan Indentification | MALDI-TOF, Q-TOF MS and FT-ICR . |
| Experimental_strategies | In vitro and In vivo |
| Acceptor Subtrate Information |
| Acceptor Substrate name | PilE |
| ProGPdb ID | ProGP99 |
| Litrature |
| Year Of Validation | 2007 |
| Reference | Chamot-Rooke, J., Rousseau, B., Lanternier, F., Mikaty, G., Mairey, E., Malosse, C., Bouchoux, G., Pelicic, V., Camoin, L., Nassif, X. & Duménil, G. (2007). Alternative Neisseria spp. type IV pilin glycosylation with a glyceramido acetamido trideoxyhexose residue. Proceedings of the National Academy of Sciences, 104(37), 14783-14788.
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| Authors | Chamot-Rooke, J., Rousseau, B., Lanternier, F., Mikaty, G., Mairey, E., Malosse, C., Bouchoux, G., Pelicic, V., Camoin, L., Nassif, X. & Duménil, G.
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| Research groups | Ecole Polytechnique, Laboratory of Reaction Mechanisms, Department of Chemistry, F-91128 Palaiseau, France
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| Corresponding Author | Duménil, G.
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| Contacts | Ecole Polytechnique, Laboratory of Reaction Mechanisms, Department of Chemistry, F-91128 Palaiseau, France
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| Reference | Musumeci, M. A., Hug, I., Scott, N. E., Ielmini, M. V., Foster, L. J., Wang, P. G., & Feldman, M. F. (2013). In vitro activity of Neisseria meningitidis PglL O-oligosaccharyltransferase with diverse synthetic lipid donors and a UDP-activated sugar. Journal of Biological Chemistry, 288(15), 10578-10587.
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| Authors | Musumeci, M. A., Hug, I., Scott, N. E., Ielmini, M. V., Foster, L. J., Wang, P. G., & Feldman, M. F.
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| Research groups | Alberta Glycomics Centre, Department of Biological Sciences, University of Alberta, Edmonton, Alberta T6G 2E9, Canada.
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| Corresponding Author | Feldman, M. F.
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| Contacts | Alberta Glycomics Centre, Department of Biological Sciences, University of Alberta, Edmonton, Alberta T6G 2E9, Canada.
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| Reference | Musumeci, M. A., Faridmoayer, A., Watanabe, Y., & Feldman, M. F. (2013). Evaluating the role of conserved amino acids in bacterial O-oligosaccharyltransferases by in vivo, in vitro and limited proteolysis assays. Glycobiology, 24(1), 39-50.
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| Authors | Musumeci, M. A., Faridmoayer, A., Watanabe, Y., & Feldman, M. F.
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| Research groups | Department of Biological Sciences, Alberta Glycomics Centre, University of Alberta, CW405 Biological Sciences Building, Edmonton, AB, Canada T6G 2E9.
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| Corresponding Author | Feldman, M. F.
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| Contacts | Department of Biological Sciences, Alberta Glycomics Centre, University of Alberta, CW405 Biological Sciences Building, Edmonton, AB, Canada.
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