ProGT44 (NGT)

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ProGT ID ProGT44 (NGT)
Organism Information
Organism NameYersinia enterocolitica strain 8081
Clinical ImplicationPathogenic
Classification Phylum : Proteobacteria
Class : GammaProteobacteria
Orders : Enterobacterales
Family : Yersiniaceae
Genus : Yersinia
Species : enterocolitica
Strain : 8081
Taxonomic ID (NCBI)393305
Genome Information
Gene BankAM286415.1
Gene Information
Protein information
Protein NameNGT 
Subcellular LocationCytoplasm
Glycosyltransferase Information
Glycosylation TypeN- (Asn) linked 
CAZY FamilyGT41
EC Number (BRENDA)2.4.1.-
Mechanism of Glycan TransferSequential
Acceptor specificity Sequon_1NX(S/T)
Donor TypeUDP-Glc and UDP-Gal ( UDP-Glc is preferred over UDP-Gal)
Donor SpecificityNucleotide activated sugars
Glycan Information
Glycan transferredMonosaccharides (Glc and Gal) 
Experimental_strategiesIn vitro 
Acceptor Subtrate Information
Acceptor Substrate name Hexapeptide DANYTK (labeled with TAMRA at the N terminus)
Year Of Validation2011 
Reference Schwarz, F., Fan, Y.Y., Schubert, M. and Aebi, M., 2011. Cytoplasmic N-glycosyltransferase of Actinobacillus pleuropneumoniae is an inverting enzyme and recognizes the NX (S/T) consensus sequence. Journal of Biological Chemistry, 286(40), pp.35267-35274.

Corresponding AuthorMolecular Biology and Biophysics, Department of Biology, ETH Zürich, 8093 Zürich, Switzerland Inst. of Microbiology, Dept. of Biology, ETH Zürich, Wolfgang-Pauli-Str. 10, 8093 Zürich, Switzerland