ProGT81 (TcnA)
| ProGT ID | ProGT81 (TcnA) |
| Organism Information | |
| Organism Name | Clostridium novyi 590 |
| Clinical Implication | Pathogenic |
| Domain | Bacteria |
| Phylum | Firmicutes |
| Classification | Family: Clostridiaceae Order: Clostridiales Class: Clostridia Phylum: Firmicutes |
| Taxonomic ID (NCBI) | 1542 |
| Genome Information | |
| Gene Information | |
| Gene Name | tcnA |
| Protein information | |
| Protein Name | TcnA |
| UniProtKB/ SwissProt ID | Q46149 |
| Glycosyltransferase Information | |
| Glycosylation Type | O- (Ser/Thr) linked |
| Mechanism of Glycan Transfer | Sequential |
| Donor Type | Nucleotide activated sugars |
| Donor Specificity | UDP-GlcNAc |
| Glycan Information | |
| Glycan transferred | Monosaccharid (GlcNAc) |
| Experimental_strategies | In vitro |
| Acceptor Subtrate Information | |
| Acceptor Substrate name | Rac1 |
| Acceptor Substrate name | RhoA |
| Acceptor Substrate name | RhoB |
| Litrature | |
| Year Of Validation | 2014 |
| Reference | Genth, H., Pauillac, S., Schelle, I., Bouvet, P., Bouchier, C., Varela?Chavez, C., Just, I. & Popoff, M. R. (2014). Haemorrhagic toxin and lethal toxin from C lostridium sordellii strain vpi9048: molecular characterization and comparative analysis of substrate specificity of the large clostridial glucosylating toxins. Cellular microbiology, 16(11), 1706-1721. |
| Authors | Genth, H., Pauillac, S., Schelle, I., Bouvet, P., Bouchier, C., Varela?Chavez, C., Just, I. & Popoff, M. R. |
| Research groups | Institute of Toxicology, Medical School Hannover, Hannover, Germany. |
| Corresponding Author | Popoff, M. R. |
| Contacts | Institute of Toxicology, Medical School Hannover, Hannover, Germany. |